Bacteroidales ⇒ Prevotellaceae {10000113}

Shared Reference Notes

• [1.1] [#Parkinson’s Disease] 
  - Prevotellaceae (Prevotella), #Ruminococcaceae (#Faecalibacterium), #Lachnospiraceae (#Blautia, #Roseburia) that produce SCFA and help in the synthesis of mucin to maintain the intestinal integrity are considerably lower in abundance in PD
• [1.2] [#Parkinson’s Disease] [#Lactobacillus] 
  - most PD patients (about 70% of patients) develop gastrointestinal disorders such as constipation, dysphagia, and gastroesophageal reflux. Strikingly, these gastrointestinal dysfunctions (particularly constipation and delayed gastric emptying) can be detected up to 20 years prior to PD diagnosis. - reduction in their number of Prevotellaceae bacteria compared to controls. Strikingly, this alteration was associated with the severity of the motor symptoms. - PD patients may exhibit not only a decreased abundance of Prevotella but also an increased abundance of Lactobacilliceae. - These alterations may be associated with reduced levels of #Ghrelin, an important gut hormone involved in the survival and efficacy of dopaminergic neurons.
• [1.3] [#Alzheimer’s disease] 
  - #Isoorientin treatment promoted the distribution of the class #Mollicutes, family Prevotellaceae, and genus Prevotellaceae UCG 001 in the fecal microbiota and the phylum Proteobacteria (Pasteurellales: Prevotellaceae ) in the cecal microbiota of AD mice
• [1.4] [#Natural Skin Microbiome] [#Human breast milk, #Infants] 
  - Infant Skin > Breastfeeding > at 3 and 6 months, respectively > lower abundances and frequencies of members of the Prevotellaceae family at both timepoints
• [1.5] 
  - in severe #Depression > reduced #Bifidobacteriaceae and Prevotellaceae with elevated #Enterobacteriaceae and #Ruminococcaceae.
• [1.6] [#Natural Small intestine Microbiome] [#Smoking] 
  - In the SI lumen, the abundance of Prevotellaceae, #Neisseriaceae, and #Porphyromonadaceae is reduced in smokers, whereas #Enterobacteriaceae and #Lactobacillaceae abundances are increased.
• [1.7] 
  - Four taxa were found to be significantly higher in blueberry treatments compared to no blueberry controls, i.e., two Actinobacteriota and listed as uncultured from the order #Coriobacteriales, one from the phylum #Bacteroidota family Prevotellaceae_UCG-001, and one from the #Firmicutes family #Anaerovoracaceae XIII_UCG-001.
• [1.8] 
  - #Sphingolipids can be produced by the intestinal symbiotic bacteria #Bacteroidetes and Prevotellaceae. - #Sphingolipids can also aggravate intestinal inflammation.
• [1.9] 
  - mucin-degraders (family Prevotellaceae) were enriched in patients with #Depression and #Anxiety
• [#Christensenellaceae] [#Short Chain Fatty Acid] - #Berberine > the relative abundances of #Parabacteroides, Prevotellaceae_UCG-001, and Prevotellaceae_NK3B31_group increased, the relative abundance of Christensenellaceae_R-7_group decreased, and cecal SCFA levels (#Acetic acid and #Propionic acid) were reduced.
• [1.11] [#Graves’ orbitopathy] [#Prevotella copri] 
  - In patients with GO, who had high levels of TRAb, the abundance of the family Prevotellaceae, and P. copri species, in particular, in the gut microbial community was correlated with TRAb levels.
• [1.12] 
  - increase in the relative abundances of #Verrucomicrobiaceae and #Akkermansia and a decrease in Prevotellaceae and #Prevotella
• [#Parkinson’s Disease] - Prevotellaceae, #Lachnospiraceae, and #Faecalibacterium were decreased significantly in patients with PD compared to healthy controls, while #Ruminococcaceae, #Bifidobacteriaceae, #Christensenellaceae, and #Verrucomicrobiaceae were enriched in patients with PD
• [1.13] [#Rheumatoid Arthritis] 
  - #High humidity intervention reduced the abundance of Prevotellaceae in healthy rats. - the abundance of Prevotellaceae decreased during the immune activation stage of CIA
• [1.14] 
  - Specific bacterial genera, including #Catenibacterium, Prevotellaceae, and #Enterobacteriaceae, enriched in PLWH > were strongly associated with accelerated biological #Aging. - These bacterial taxa can catabolize #Tryptophan and were correlated with elevated levels of the metabolic byproducts of #Tryptophan catabolism. Increased #Tryptophan catabolism leads to an accumulation of toxic metabolic byproducts such as #kynurenine and #Quinolinic acid. - These byproducts have been linked with adverse outcomes in chronic #HIV infection
• [1.15] [#Prevotella copri] [#Homosexuality] 
  - men who have sex with men (MSM) gut microbiomes are frequently dominated by members of the Prevotellaceae family, including co-colonization of species from the Segatella copri complex and unknown Prevotellaceae members.
• [1.16] [#High temperature and humidity] 
  - HTH caused a distinct alteration of gut microbiota charactered as increased #Firmicutes/ #Bacteroidetes ratio, decreased Prevotellaceae UCG-001 accompanied with increased #Lachnoclostridium and #Candidatus saccharimonas at day 7. Prevotellaceae UCG-001, involved in saccharolytic fermentation, probably contributed to the decreased plasma #Butyric acid level. - the decreased #Butyric acid recovered rapidly and could not explain the #GLP-1 suppression as butyrate supplement could not alleviate #GLP-1 decline

References Notes