Clostridiales ⇒ Christensenellaceae {10000911}

Shared Reference Notes

• [1.1] 
  - Christensenellaceae was negatively correlated with the consumption of cookies and pastries, but only in individuals with a gut microbiome enriched in Bacteroides.
• [1.2] [#Inflamatory bowel disease] 
  - In IBD > reduced levels of Christensenellaceae, #Odoribacter, #Mogibacteriaceae and #Gemmiger and increased abundance of #Peptostreptococcaceae.
• [1.3] [#Depression] [#Coprococcus eutactus, #Lachnospiraceae] 
  - RuminococcaceaeUCG005 as the most important genus in predicting depressive symptoms. - #Sellimonas, #Eggerthella, #Lachnoclostridium and #Hungatella were more abundant in individuals with higher depressive symptoms. - 12 genera and 1 microbial family associated with depressive symptoms > genera #Sellimonas, #Eggerthella, #Ruminococcaceae (UCG002, UCG003, UCG005), #Lachnoclostridium, #Hungatella, Coprococcus, LachnospiraceaeUCG001, Ruminococcusgauvreauiigroup, #Eubacterium ventriosum, #Subdoligranulum and family #Ruminococcaceae.
• [1.4] [#Short Chain Fatty Acid] 
  - in #Centenarians, longevity is positively associated with an abundance of short-chain fatty acid (SCFA) producers, such as #Clostridium cluster XIVa, #Ruminococcaceae, #Akkermansia, and Christensenellaceae
• - good immunological and metabolic health-related bacteria, such as #Akkermansia, Christensenellaceae, and #Lactobacillus, were higher in #Centenarians than in other groups
• [1.5] [#Actinobacteria] 
  - #Anorexia nervosa > lowered Actinobacteriota and #Bacteroidota counts. - Among families of bacteria, Christensenellaceae species, particularly CAG-138, showed the most significant enrichment in AN.
• [1.6] [#Metabolic associated fatty liver disease] 
  - Christensenellaceae, and #Intestinibacter were negatively correlated with non-alcoholic fatty liver disease.
• [1.7] [#Prostate cancer] [#Short Chain Fatty Acid] 
  - #Subdoligranulum, #Lachnobacterium, Christensenellaceae, #Lachnospira, #Rikenellaceae, #Eggerthella, and #Alistipes are members of the SCFA-producing order #Clostridiales and were shown to be more prevalent in individuals with high-grade PCA.
• [1.8] [#Prevotellaceae] [#Short Chain Fatty Acid] 
  - #Berberine > the relative abundances of #Parabacteroides, Prevotellaceae_UCG-001, and Prevotellaceae_NK3B31_group increased, the relative abundance of Christensenellaceae_R-7_group decreased, and cecal SCFA levels (#Acetic acid and #Propionic acid) were reduced.
• [1.9] [#Creutzfeldt–Jakob disease] 
  - Several bacteria taxa in sCJD patients were increased at genus level, such as #Turicibacter, norank_f_Christensenellaceae, #Eisenbergiella, #Bilophila and #Holdemania.
• [#Parkinson’s Disease] - #Prevotellaceae, #Lachnospiraceae, and #Faecalibacterium were decreased significantly in patients with PD compared to healthy controls, while #Ruminococcaceae, #Bifidobacteriaceae, Christensenellaceae, and #Verrucomicrobiaceae were enriched in patients with PD
• [1.11] [#Autism] [#Eubacterium coprostanoligenes] 
  - in contrast to ASD Patient > #Oscillospiraceae , Christensenellaceae, Eubacterium coprostanoligenes_group, Oscillospirales__UCG-010and #Selenomonadaceae, generally enriched in SIB and GP groups were negatively correlated with #Propionic acid.
• [#Eubacterium coprostanoligenes] - #Acetic acid correlated negatively with #Veillonellaceae, #Oscillospiraceae, Christensenellaceae, Eubacterium coprostanoligenes_group , #Candidatus gastranaerophilales and Oscillospirales_UCG-010.
• [1.12] [#Phenylacetylglutamine] 
  - circulating PAG levels to different families of gut microbes such as #Coriobacteriaceae, #Mogibacteriaceae, #Bifidobacteriaceae, with genera in the #Lachnospiraceae, Christensenellaceae and #Ruminococcaceae families and with gut microbiome diversity.
• [1.13] [#Colon adenomas, #Colon polyps] [#Oscillospiraceae] [#α-glucosidase] 
  - intetinal adenoma > higher abundance of Christensenellaceae_R-7 group and Oscillospiraceae_UCG-002 were found in fecal samples displaying low α-glucosidase activity

References Notes