Disease ⇒ Vitamin D deficiency {40000165}

Record Keys
Type:	Disease
Parent:	[ ]
Definition:	Vitamin D deficiency

Details
Initialisation date:	2019-06-16
Other Terms:	Hypovitaminosis D

Links
Wickipedia Merck Manual

Meta Information
MedDra ID:	[ ]
MedDra Level:	[ ]
ICD:	[ ]
Category:	Musculoskeletal, Endocrinology, Neonatology, Obstetrics
Zone:	[ ]
Mechanism:	[ ]

Notes:

- Increased proportional abundance of Sneathia amnii, Prevotella-related clades, Lachnospiraceae BVAB1, Saccharibacteria TM7-H1.
- These taxa were also associated with low levels of vitamin D63, suggesting that the vaginal microbiome might mediate a link between Preterm Birth risk and vitamin D deficiency (1)

Shared Reference Notes

[1.1]
- Vitamin D deficiency produces intestinal dysbiosis, with a reduction of bacteria with anti-inflammatory properties (e.g., #Firmicutes) and an increase in pathobiontic bacteria (e.g., Bacteroides and Proteobacteria).
[1.2] [#Chronic Musculoskeletal Pain, #Fibromyalgia, #Vitamin D deficiency-mediated chronic pain]
- 25OHD supplementation results in pain reduction. Our results suggest a possible role of #Vitamin D supplementation in alleviating the pain associated with FMS and CMP, especially in #Vitamin D-deficient individuals.
[1.3] [#Parkinson’s Disease]
- lack of #Vitamin D also leads to central loss of dopaminergic neurons, as well as delayed gastric emptying in PD
[1.4] [#Colorectal cancer]
- #Vitamin D deficiency is associated with an increased CRC risk.
[1.5] [#Celiac Disease]
- #Vitamin D deficiency was observed in both Celiac NRCD clusters, suggesting its relevance in the context of NRCD.

References Notes

[1.7]

Common References

[1.1] Inflammatory Bowel Diseases: Is There a Role for Nutritional Suggestions? [2021] [Review] [Nutrients] [Journal] [80001802]
[1.2] The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musculoskeletal Pain [2022] [Review] [Nutrients] [Journal] [80002510]
[1.3] Nutrition and Gut–Brain Pathways Impacting the Onset of Parkinson’s Disease [2022] [Review] [Nutrients] [Journal] [80002546]
[1.4] Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice [2023] [Study] [Cancer Cell] [Journal] [80003156]
[1.5] Non-responsive Celiac disease symptoms associated with microbiome network structure and function [2023] [80003550]
[1.6] Association of Gut Microbiome and Vitamin D Deficiency in Knee Osteoarthritis Patients: A Pilot Study [2021] [Research] [Nutrients] [Journal] [80001797]
[1.7] The Integrative Human Microbiome Project [2019] [Report] [Nature] [Journal] [80000046]

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Disease ⇒ Vitamin D deficiency {40000165}

Record Keys

Details

Links

Meta Information

Notes:

Shared Reference Notes

References Notes

Common References