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Disease ⇒ Constipation {40000270}

Record Keys


Type:
Disease
Parent:[  ]
Definition:
Constipation

Details


Initialisation date:
2021-02-11
Other Terms:[  ]

Meta Information


MedDra ID:
10010774
MedDra Level:
pt
ICD:[  ]
Category:
Gastroenterology
Zone:[  ]
Mechanism:[  ]

Notes:


- Constipation may predispose to different dysbiome related to other chronic diseases.

Shared Reference Notes


  • [1.1] [#Consumption of Magnesium oxid
    - Mg2+ oxide > Decrease in stool consistency and suppressed presence of the genus #Dialister
  • [1.2] [#Parkinson’s Disease
    - #Tryptophan, an essential amino acid only derived from microbiome or diet, is the rate limiting precursor to #Serotonin. #Tryptophan biosynthesis pathway was reduced in PD. - spore forming bacteria modulate #Serotonin production and enhance gut motility - constipation, a common symptom of PD, may be related to the depletion of spore forming bacteria.

References Notes


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