Lachnospiraceae ⇒ Marvinbryantia {10000796} Record Keys Parent:Lachnospiraceae Definition:Marvinbryantia Details Initialisation date:[ ] Meta Information Rank: Genus Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Diabetes Type 2] [#Short Chain Fatty Acid] - In four other genera (#Fusicatenibacter, #Agathobacter, #Butyricicoccus, Marvinbryantia), a decrease in the T2D group could also be detected. All genera produce short-chain fatty acids [1.2] [#Diabetes Type 2] [#Short Chain Fatty Acid] - A few examples of SCFA-producing bacteria are #Blautia hydrogenotrophica and Marvinbryantia formatexigens, #Veillonella spp., #Dialister spp etc. - Levels of SCFAs in T2DM patients are always lower than the healthy subjects. - The mechanism of action of SCFA includes promoting insulin secretion, improving insulin sensitivity, activating intestinal gluconeogenesis, increasing energy expenditure, reducing fat accumulation and inflammation. - They promote the production of satiety hormones and reduce the feeling of appetite. [1.3] [#mRNA vaccine] - #Methanobrevibacter, #Ruminococcaceae #DTU089, Marvinbryantia, #Cloacibacillus, and #Succinivibrio were enriched in the baseline microbiome of individuals with low IgG titers and low spike-specific CD4+ T-cell responses. [#Covid-19] [#Short Chain Fatty Acid] [#mRNA vaccine] - Marvinbryantia was observed to be less abundant in the younger group. - enrichment of Marvinbryantia spp., which are SCFA-producers, in the elderly > a lower response to vaccinations,References Notes[ ]