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Microbiome & Chronic Diseases

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Roseburia ⇒ Roseburia intestinalis {10000245}

Record Keys


Parent:
Definition:
Roseburia intestinalis

Details


Initialisation date:
2020-09-25

Meta Information


Rank:
 Species
Domain:
 Bacteria
Zone:[  ]
Enzyme:[  ]
Function:
Starch-degrading

Notes:


- R intestinalis is a major contributors to starch degradation V.

Shared Reference Notes


  • [1.1
    - the abundance of Roseburia intestinalis is negatively correlated with the size of atherosclerotic lesions in the mouse model of #Atherosclerosis. - when Roseburia intestinalis was taken along with a high-fiber diet, aortic atherosclerotic plaques were reduced in size. This study suggests that the butyrate, a microbial metabolite, mediates these effects
  • - The most prominent butyrogenic bacteria groups are #Faecalibacterium prausnitzii, #Butyrivibriocrossotus and Roseburia intestinalis which several studies have reported the depletion of these bacteria in atherosclerosis
  • [1.2
    - Roseburia intestinalis specifically able to metabolize the indigestible glycans β-mannans found in #Nuts into #Butyrate
  • [1.3
    - Roseburia intestinalis produces butyrate and flagellin to influence the balance of Treg and Th17 cells.
  • [1.4] [#Parkinson’s Disease
    - At one end of the spectrum, #Bifidobacterium dentium was elevated by 7-fold, #Actinomyces oris by 6.5-fold, #Streptococcus mutans by 6-fold. At the other end of the spectrum, Roseburia intestinalis was reduced by 7.5-fold, and #Blautia wexlerae by 5-fold.

References Notes


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Common References