Adlercreutzia ⇒ Adlercreutzia equolifaciens {10000202}

Shared Reference Notes

• [1.1] 
  - #Proanthocyanidins are biotransformed by Adlercreutzia equolifaciens JCM 14793T, #Eubacterium sp. SDG-2, #Eggerthella lenta rK3 and #Eggerthella lenta CAT-1 and from the phylum actinomycetes, which belong to the phylum #Actinobacteria, through the cleavage of the C-ring and dihydroxylation reactions to produce (−)EGC, (−)-gallocatechin (GC), (±)EC and (±)-catechin (C)
• [1.2] [#Alzheimer’s disease] [#Enterobacteriaceae bacterium] 
  - AD elders were also depleted in Adlercreutzia equolifaciens, an #Equol-producing bacterium, which has beneficial effects in reducing experimental cutaneous inflammation in mice and the loss of which has been associated with the neurodegenerative disorder #Multiple Sclerosis.
• [1.3] 
  - Specific bacterial strains that have the ability to process dietary #Polyphenols have been identified and include #Eubacterium ramulus, Adlercreutiza equolifaciens and #Flavonifractor plautii
• [1.4] [#Soybean] 
  - A. equolofaciens produces the nonsteroidal #Estrogen #Equol from isoflaven found in soybeans
• [#Cognitive impairment] - A. equolofaciens subspecies celatus was also the most important features in RF models of the right anterior cingulate, which has been linked to social cognition and reward-based decision making - estrogen has previously been shown to have activity in this brain region
• [1.5] [#Chronic liver disease, #Metabolic associated fatty liver disease] 
• [1.6] [#Autism] 
  - Several known #Equol producers were consistently higher in controls, including #Slackia and Adlercreutzia equolifaciens. #Coriobacteriaceae, a family involved in lipid metabolism85 and #Equol production, was also depleted in #Infants with future NDs. - significant decrease in a potential #Equol signal in future ASD cases.

References Notes