humanized Galactooligosaccharides {90000157}

Shared Reference Notes

• [1.1] 
  - #Probiotic #Bifidobacterium breve, plus the prebiotic galactooligosaccharides (GOS) > increased facial skin hydration (corneometer) and improved overall facial skin appearance (Visual Analog Scale) > lower urinary levels of phenol and p-cresol, presumably due to a beneficial effect of the study drink on gut flora.
• - oral consumption of a prebiotic containing lactulose plus GOS > a reduction in measured facial wrinkle length and depth. - GOS > corneometer values were significantly greater in the treated group than in the control group > TEWL in the treated group also significantly improved.
• [1.2] [#Depression] [#Bifidobacterium animalis lactis, #Bifidobacterium bifidum, #Bifidobacterium longum, #Lactobacillus acidophilus] [#Combination of probiotics and polyphenol-rich prebiotics] 
  - patients were administered a synbiotic containing L. acidophilus, B. bifidum, B. lactis, and B. longum with the prebiotics FOS, GOS and #Inulin. In a subset of patients with depressive symptoms, the synbiotic significantly reduced the depressive score compared to both the #Probiotic-alone and placebo groups, which correlated to an increase in #BDNF serum levels.
• [#Short Chain Fatty Acid] [#Fructooligosaccharides] - prebiotics that promote SCFA production such as #Fructooligosaccharides (FOS), galactooligosaccharides (GOS) or #Inulin, have been shown to have multiple beneficial immune- and metabolic- effects that can ultimately improve cognition.
• [1.3] 
  - #Lactobacillus and #Bifidobacterium specialize in oligosaccharide fermentation, utilizing galactooligosaccharides (GOS), #Fructooligosaccharides (FOS), and #Polysaccharide #Inulin
• [1.4] [#Osteoporosis] 
  - the prebiotic galactooligosaccharides (GOS) promotes the growth of #Bifidobacteria which increases calcium absorption and prevents bone loss and enhances calcium absorption and inhibits bone resorption in #Postmenopausal women
• [1.5] [#Fructooligosaccharides] 
  - #Actinobacteria, #Bacteroidetes, and #Firmicutes, can ferment FOS, GOS, and xylooligosaccharides (XOS).
• - In #Infants, GOS reduces the risk of #Atopic Dermatitis and eczema
• - GOSs can greatly stimulate #Bifidobacteria and #Lactobacilli. #Bifidobacteria in #Infants have shown high incorporation with GOS. Enterobacteria, #Bacteroidetes, and #Firmicutes are also stimulated by GOS, but to a lesser extent than #Bifidobacteria
• - GOS increased the blood level of interleukin 8 (#IL-8), interleukin 10 (#IL-10), and #C-reactive protein in adults, but decreased IL-1β. It has been found that the function of NK cells improves by consuming GOS.
• - Fructo-oligosaccharides (FOS), galacto-oligosaccharides (GOS), and trans-galacto-oligosaccharides (TOS) are the most common prebiotics
• [#Irritable bowel syndrome] [#Fructooligosaccharides] - IBS symptoms improvement after consuming 5 g/day FOS for 6 weeks [101] or 3.5 g/day GOS for 12 weeks

References Notes