Lab ⇒ Serum CRP {40000567} Record Keys Type:Disease, Lab Parent:[ ] Definition:Serum CRP Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone: Blood Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - serum 25(OH)D had an L-shaped association with serum CRP, where CRP levels decreased sharply with increasing 25(OH)D concentration for participants within the deficiency range. - #Vitamin D can inhibit the production of pro-inflammatory cytokines such as interleukin-12 (IL-12) promoting, at the same time, the production of the anti-inflammatory cytokines IL-10. [1.2] - #TMAO activates NLRP3 and increases reactive oxygen species formation. - The level of circulating #TMAO correlates with that of C-reactive protein, an inflammation indicator. [1.3] [#Bipolar disorder] - serum CRP concentration was positively correlated with #Prevotella abundance, but negatively correlated with #Butyricicoccus, #Lachnospiraceae incertae sedis and #Dorea abundance in BD patients. [#Serum triglycerides] - The abundance of #Prevotella was positively associated with serum levels of triglycerides (TG) and high-sensitive CRP (hs-CRP) - As a #Butyrate-producing bacteria, #Butyricicoccus was positively correlated with anti-inflammatory cytokines such as IL-4, #IL-10, and IL-11. - The negative association between CRP and #Butyricicoccus abundance may reflect an imbalance between pro- and anti- inflammatory reactions. [1.4] - Patients with axial #Spondyloarthritis (SpA), #Acute anterior uveitis (AAU), and #Crohn’s disease > low abundances of #Lachnospiraceae taxa relative to controls, most notably #Fusicatenibacter, which was most abundant in controls receiving NSAID monotherapy and implied to partially mediate higher serum CRP.References Notes[ ]
