Vancomycin {50000132} Record Keys Definition:Vancomycin Queue:[ ] Details Initialisation date:2019-08-25 Specification: [ ] LinksInfolink Meta Information Type:Antibiotic Host: Mouse Zone:[ ] Notes: - Vancomycin-treated mice showed an increase in Lactobacillus animalis in the gut, whereas there was a depletion in the total gut bacterial load. (1)Shared Reference Notes [1.1] [#Diabetes Type 2] [#High Fat Diet] - HFD caused a decrease in circulating GLP-1 levels, and this was reversed with vancomycin treatment [1.2] [#Clostridium difficile associated disease] - vancomycin is used for C. difficile (CDI) which is associated with decrease in number of gut microbes like #Bacteroidetes, #Fuminococcus, and #Faecalibacterium and increases in #Proteobacteria species. [1.3] [#Enterococcus faecium, #Staphylococcus aureus] - #Clovibactin efficiently kills drug-resistant Gram-positive bacterial pathogens without detectable resistance. - #Clovibactin exhibited antibacterial activity against a broad range of Gram-positive pathogens, including methicillin- resistant S. aureus (MRSA), daptomycin-resistant and vancomycin intermediate resistant S. aureus (VISA) strains, and difficult to treat vancomycin resistant #Enterococcus faecalis and E. faecium (vancomycin-resistant enterococci [VRE]). [1.4] [#Antibiotic Therapy] - #Bifidobacteria metabolize #lactulose, produce high concentrations of #Acetate and acidify the gut lumen in humans and mice, which, in combination, can reduce the growth of antibiotic-resistant bacteria such as vancomycin-resistant #Enterococcus faecium in vitro.References Notes[ ]
