Phenylacetylglutamine {90000368}
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| Definition: | Phenylacetylglutamine |
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Shared Reference Notes
- [1.1] [#Atherosclerosis, #CVD]
- gut microbiota-dependent metabolism of dietary #Phenylalanine into #Phenylacetic acid (PAA) is critical in phenylacetylglutamine (PAGln) production, a metabolite linked to atherosclerotic cardiovascular disease (ASCVD). - PPFOR is the main contributor for PAA production in #Bacteroides thetaiotaomicron. - PPDC plays an important role in PAA generation in #Proteus mirabilis. - PPFOR and PPDC contribute to PAA production and PAGln formation in colonized hosts. - Gut microbial ppdc and ppfor homolog abundances are each associated with ASCVD in humans.
References Notes
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