Disease ⇒ Creutzfeldt–Jakob disease {40000631} Record Keys Type:Disease Parent:[ ] Definition:Creutzfeldt–Jakob disease Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - The sCJD patients showed significant differences in the composition of gut microbiota and metabolites relative to the healthy controls. [#Christensenellaceae] - Several bacteria taxa in sCJD patients were increased at genus level, such as #Turicibacter, norank_f_Christensenellaceae, #Eisenbergiella, #Bilophila and #Holdemania. - the metabolites related to the biosynthesis of phenylpropanoids, especially #Biochanin A, showed the most obvious decrease in the sCJD group - metabolites in sCJD, related to #Linoleic acid metabolism and steroid hormone biosynthesis might be biomarkers of evaluating disease severity.References Notes[ ]
