Methylobacteriaceae ⇒ Saccharibacteria {10000304} Record Keys Parent:Methylobacteriaceae Definition:Saccharibacteria Details Initialisation date:2020-10-13 Meta Information Rank: Genus Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Periodontal disease] - Saccharibacteria species > reduce inflammation and consequential bone loss by modulating host bacterial pathogenicity in a mouse ligature-induced periodontitis model. [1.2] [#Alzheimer’s disease] [#Atopobium rimae, #Bacteroides-Prevotella group, #Prevotella nigrescens, #Prevotella oulorum, #Treponema socranskii, #prevotella salivae] - subgingival samples of the AD group showed significant increases in the abundance of bacterial species potentially linked with periodontitis, such as A. rimae, Saccharibacteria (#TM7) HMT 348, #Selenomonas sp. HMT 442, T. socranskii and various #Prevotella spp., such as P. maculosa, P. multiformis, P. nigrescens, P. oulorum and P. salivae, which could aggravate systemic diseases. [#Alzheimer’s disease] - potential periodontal pathogens such as #Prevotella, Saccharibacteria (#TM7), #Treponema and #Selenomonas spp. were significantly more abundant in the AD group, especially in subgingival plaque. - #Prevotella spp. were densely interconnected with various oral microbiome. [1.3] [#Parkinson’s Disease] [#Bacteroides-Prevotella group] - #Mycoplasma faucium, #Tannerella forsythia, #Parvimonas micra, and Saccharibacteria (#TM7) were increased in P; #Prevotella pallens, #Prevotella melaninogenica, #Neisseria multispecies were more abundant in PA+P group, #Ruthenibacterium lactatiformans, #Dialister succinatiphilus, #Butyrivibrio crossotus and #Alloprevotella tannerae were detected in fecal samples in P groups compared to healthy controls.References Notes[ ]