Parvimonas ⇒ Parvimonas micra {10000286}

Shared Reference Notes

• [1.1] [#Colorectal cancer] 
  - four species of two genera are found to be associated with CRC: #Parvimonas micra, #Parvimonas sp., #Peptostreptococcus stomatis, and #Peptostreptococcus anaerobius.
• [1.2] 
  - Parvimonas micra, #Haemophilus influenzae, #Fusobacterium periodonticum, #Streptococcus constellatus, and #Filifactor alocis progressively increased with #Oral cancer development.
• [1.3] 
  - grade 3 tumors #Colorectal cancer were significantly enriched in #Fusobacterium and #Parvimonas - #Parvimonas micra and #Fusobacterium have been shown to aggregate and form biofilms in vitro. - Biofilm formation is linked to inflammatory bowel disease and CC.
• [1.4] [#Colorectal cancer] 
  - The elevated abundance of certain bacterial species such as #Fusobacterium nucleatum and Parvimonas micra in CRC patients is often associated with the development of the disease.
• [1.5] [#Colorectal cancer] [#Porphyromonas gingivalis] [#Butyrate] 
  - In the intestine, oral-derived microbiotas create an inflammatory and immunosuppressive microenvironment suitable for tumorigenesis. It is detected the existence of oral-originated bacteria (#Fusobacterium nucleatum, P. gingivalis, and Parvimonas micra) in CRC tissues.
• [1.6] 
  - #Cancer-associated bacteria are #Fusobacterium nucleatum, #Peptostreptococcus stomatis, and Parvimonas micra
• [1.7] [#Parkinson’s Disease] [#Bacteroides-Prevotella group] 
  - #Mycoplasma faucium, #Tannerella forsythia, Parvimonas micra, and #Saccharibacteria (#TM7) were increased in P; #Prevotella pallens, #Prevotella melaninogenica, #Neisseria multispecies were more abundant in PA+P group, #Ruthenibacterium lactatiformans, #Dialister succinatiphilus, #Butyrivibrio crossotus and #Alloprevotella tannerae were detected in fecal samples in P groups compared to healthy controls.
• [1.8] [#Colorectal cancer] [#Teenager] 
  - well-known CRC-associated taxa, such as #Clostridium symbiosum, #Peptostreptococcus stomatis, Parvimonas micra and #Hungatella hathewayi were significantly enriched in both old- and young-onset patients. - Similar strain-level patterns of #Fusobacterium nucleatum, #Bacteroides fragilis and #Escherichia coli were observed for oCRC and yCRC. - Almost all oCRC-associated metagenomic pathways had directionally concordant changes in young patients.
• [1.9] [#Colorectal cancer] 
  - #Fusobacterium nucleatum, did not significantly associate with CRC diagnostic groups (healthy, adenoma and carcinoma) when controlling for covariates transit time, fecal #Calprotectin (intestinal inflammation) and body mass index as primary microbial covariates. - In contrast, the associations of #Anaerococcus vaginalis, #Dialister pneumosintes, Parvimonas micra, #Peptostreptococcus anaerobius, #Porphyromonas asaccharolytica and #Prevotella intermedia remained robust, highlighting their future target potential.

References Notes