Disease ⇒ Atopy {40000206} Record Keys Type:Disease Parent:[ ] Definition:Atopy Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:10003645 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - Newborns who develop immunoglobulin E (IgE)-mediated allergic sensitization (atopy) by 1 year of age have a less-diverse gut metabolome at birth. [1.2] - There is an expansion of #Candida sp. and Rhodotorula sp. in stool samples from US infants that later developed atopy. [1.3] [#Early-life cytomegalovirus infection] - Early CMV infection > increased beta and decreased alpha diversity of the gut microbiota > persistent allergic sensitization at age 5 years [1.4] [#Allergy, #Atopic Dermatitis] - In #Children with AD, there was a significantly lower #Vitamin D level at age 2 and 4, but a significantly higher prevalence of food and mite sensitization at all ages in comparison with HC. - #Vitamin D level was found to be inversely related to the prevalence of allergen sensitization at age 4 References Notes[ ]
