Roseburia ⇒ Roseburia hominis {10000102} Record Keys Parent:Roseburia Definition:Roseburia hominis Details Initialisation date:2020-09-06 LinksSource Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Crohn’s disease] [#Escherichia coli] [#Fecal Microbiota Transplantation] - Comprehensive overview of functional dysbiosis in the gut microbiome during IBD activity showed increases in facultative anaerobes, such as E. coli which correlates with inflammation status, and decreases in obligate anaerobes, such as #Faecalibacterium prausnitzii and Roseburia hominis -The results of the present study confirmed decreases in the abundance of Firmicutes and Bacteroidetes, increases in Enterobacteriaceae, Pasteurellaceae, and Veillonellaceae and the presence of Fusobacterium in stool samples of CD patients. - #Butyrate-producing bacteria are depleted in IBD patients, and probiotic treatment with these bacteria has therapeutic potential. - A higher proportion of #Lachnospiraceae in donor stool was associated with a higher success rate of FMT, and recipients that responded to FMT exhibited increases in #Butyrate-producing #Lachnospiraceae and Ruminococcaceae. - The reduced SCFA levels in patients with IBD result from lower abundance of SCFA-producing bacteria, especially those of the phylum Firmicutes. - #Butyrate can act as an energy source for normal colon epithelial cells, promoting their proliferation, but can also inhibit proliferation and induce apoptosis. [1.2] [#Mild Cognitive Impairment] - the abundance of #Butyrate producing bacteria such as #Lachnospiraceae family, #Subdoligranulum sp., #Roseburia intestinalis, and Roseburia hominis were reduced in the gut of MCI participants compared to cognitively healthy controls. [1.3] [#Juvenile idiopathic arthritis] - In JIA > reduced #Anaerostipes, #Dialister, #Lachnospira, and #Roseburia have been correlated with rheumatic clinical indices including antibodies, erythrocyte sedimentation rate (ESR) and clinical JIA disease activity score. - #Dialister, #Lachnospira, and #Roseburia (#Roseburia hominis in 0% of ABISJIA) were three of five genera reduced in ABISJIA, as well as an ASV belonging to #Anaerostipes.References Notes[ ]
