Lauric acid {90000425} Record Keys Parent:[ ] Definition:Lauric acid Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:Lipid Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - lauric acid was shown to exert antimicrobial activity against #Cutibacterium acnes [1.2] [#Cutibacterium acnes] - lipid extracted from neonatal human epidermal keratinocytes (NHEKs) after exposure to C. acnes CM or #Propionic acid has increased antimicrobial potency against C. acnes. - Many lipids potentially made by NHEK have antimicrobial activity including lauric acid, #Palmitoleic acid isomer (C16:1Δ6), sphingosine, and dihydrosphingosine [1.3] [#Lactobacillus plantarum] [#Lead] - L. plantarum CCFM8661 alleviate Pb toxicity by changing microbiota and metabolites > increase of #Bifidobacterium and decrease of #Bilophila > Increased metabolites include #Taurine and #Xanthine in colon, lauric acid in serum. [1.4] [#Helicobacter pylori] [#Monolaurin ] - lauric acid is the main antibacterial and antiviral substance found in breastmilk and in the gut is enzymatically broken down to form monolaurin, a monoester with profound anti-microbial and anti-fungal properties against lipid-coated bacteria, including inactivation of H. pylori and #Listeria monocytogenesReferences Notes[ ]
