Guar gum {51111352}
| Definition: | Guar gum |
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| Queue: | [ ] |
| Initialisation date: | [ ] |
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| Specification: | |
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| Type: | Diet |
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| Host: | Human |
| Zone: | [ ] |
Notes:
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Shared Reference Notes
- [1.1] [#Multiple Sclerosis] [#Short Chain Fatty Acid]
- Individual dietary fiber sources have distinct impacts on T cell subsets - The dietary fiber guar gum impairs Th1 polarization and alters migratory potential - Guar gum elevates short-chain fatty acids but does not impact regulatory T cells - Guar gum supplementation significantly delays autoimmune neuroinflammation - [1.2]
- guar gum primarily enriches Actinobacteriota, specifically #Bifidobacterium. - [#Antibiotic Therapy] - guar gum containing diet (GuD) increased the susceptibility to colonic inflammation. - Amelioration of #Colitis in GuD-fed group pre-treated with antibiotics suggest a vital role of intestinal microbiota in GuD-mediated exacerbation of intestinal inflammation.
- - Colonic #IL-18 and tight junction markers were also decreased in the GuD-fed group.
- - Guar gum > luminal accumulation of intermediary metabolites #Succinate and #Lactate in the GuD-fed mice.
- [1.3]
- soluble fiber #Inulin or guar gum, but not insoluble fiber cellulose, promoted colorectal tumorigenesis in AOM-treated and Apcmin/+ mice. - Soluble fiber induced gut dysbiosis with #Bacteroides uniformis enrichment and #Bifidobacterium pseudolongum depletion, accompanied by increased fecal #Butyrate and serum #Bile Acids and decreased #Inosine.
References Notes
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