MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine
Sign in

Bile Acids ⇒ Glycoursodeoxycholic acid {90000409}

Record Keys


Parent:
Definition:
Glycoursodeoxycholic acid
Queue:[  ]

Details


Initialisation date:[  ]
Specification:

GUDCA

Source:
[  ]

Meta Information


Structural Type:[  ]
Functional Type:[  ]
Function:[  ]

Notes:


[  ]

Shared Reference Notes


  • [1.1] [#Diabetes Type 2] [#Oral administration of Metformin
    - GUDCA, an endogenous bile acid conversed by gut bacteria, was found to be increased by metformin treatment and improve insulin sensitivity though an intestinal FXR dependent pathway
  • [1.2] [#Anorexia nervosa, #Bulimia nervosa] [#Bacteroides uniformis
    - Individuals with AN lacking the genomic region of B. uniformis had greater scores for self-denial and bulimia. - The genetic deletion in B. uniformis could result in the deficiency of thiamine, a vitamin associated with intestinal and mental health. - The #Serotonin synthesis module causally affected BMI through glycoursodeoxycholic acid, which is upregulated by #Serotonin.

References Notes


[  ]

Common References