Bile Acids ⇒ Glycoursodeoxycholic acid {90000409}
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| Definition: | Glycoursodeoxycholic acid |
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GUDCA | |
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Shared Reference Notes
- [1.1] [#Diabetes Type 2] [#Oral administration of Metformin]
- GUDCA, an endogenous bile acid conversed by gut bacteria, was found to be increased by metformin treatment and improve insulin sensitivity though an intestinal FXR dependent pathway - [1.2] [#Anorexia nervosa, #Bulimia nervosa] [#Bacteroides uniformis]
- Individuals with AN lacking the genomic region of B. uniformis had greater scores for self-denial and bulimia. - The genetic deletion in B. uniformis could result in the deficiency of thiamine, a vitamin associated with intestinal and mental health. - The #Serotonin synthesis module causally affected BMI through glycoursodeoxycholic acid, which is upregulated by #Serotonin.
References Notes
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