Disease ⇒ Hypertension ⇒ Gestational Hypertension {40000184} Record Keys Type:Disease Parent:Hypertension Definition:Gestational Hypertension Details Initialisation date:2020-10-04 Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:Cardiovascular, Obstetrics Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Hypertension] - #Bacillus was associated with high blood pressure [#Hypertension] - a negative association between #Shewanella and Diastolic BP. - #Shewanella, commonly known as an environmental bacteria, has recently been reported to play an important role in multiple drug resistances [#Preeclamsia] - the relative abundance of #Methanobrevibacter is higher in healthy controls than in HDP cases during both early and late pregnancies. - It is not the composition of the whole GM, but maybe some certain taxa that change during #Pregnancy and have effects on HDP. - the relative abundance of #Polycyclovorans and #Pelomonas in GH / PE in early #Pregnancy was significantly higher than that in healthy control, and these bacteria were also enriched in the late trimester of GH / PE patients. [1.2] - The abundance of the butyrate-producing genus Odoribacter was inversely correlated with systolic blood pressure. - In obese pregnant women, butyrate production capacity is decreased, but plasminogen activator inhibitor-1 concentrations increased. - Plasminogen activator inhibitor-1 levels were inversely correlated with expression of butyrate kinase and Odoribacter abundance. - In overweight and obese pregnant women at 16 weeks gestation, the abundance of butyrate-producing bacteria and butyrate production in the gut microbiota is significantly negatively associated with blood pressure and with plasminogen activator inhibitor-1 levels.References Notes[ ]
