Silymarin {51111452} Record Keys Definition:Silymarin Queue:[ ] Details Initialisation date:[ ] Specification: [ ] Meta Information Type:Diet, Drug Host:[ ] Zone:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Akkermansia muciniphila] [#Flavonoid] - silymarin/#Silibinin > dietary flavonoids or #Polyphenols > increase of ASV5 (A. muciniphila) [#Bilophila wadsworthia] [#High Fat Diet] - HFD-induced increase of (B. wadsworthia) which is bile-tolerant was further aggravated by silymarin/#Silibinin treatment. - B. wadsworthia was sensitive to the environmental redox changes as the abundance of this bacterium was also found largely increased in vitro upon exposure of #Metformin - abundance of #Escherichia/#Shigella was found increased by both silymarin and #Metformin [#Obesity] [#Vitamin B12] - silymarin and resulted bacterial B12 improved the liver lipid metabolism via suppressing lipogenesis and enhancing fatty acid oxidation. [#Vitamin B12] - silymarin treatment was associated with B12 biosynthesis and increased concentration of fecal as well as plasma B12 > due to bacterial biosynthesis [#Vitamin B12] - lipid metabolism by silymarin-adapted microbiota mainly attributed to bacterial B12 biosynthesis.References Notes[ ]