Acetylcholine {90000146}
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Definition: | Acetylcholine |
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Functional Type: | Neurotransmitter |
Function: | Anti-inflammatory |
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Shared Reference Notes
- [1.1]
- #Lactobacillus can produce acetylcholine - [1.2]
- Acetylcholine is produced from #Lactobacillus - [1.3] [#Lipopolysaccharide]
- Vagus nerve stimulation decreases the neuroinflammatory response to systemic administration of lipopolysaccharides and induces an anti-inflammatory microglial phenotype in an AD model. - Stimulation of the vagus nerve > release acetylcholine, which has an anti-inflammatory effect on macrophage gene expression in the periphery. - [1.4] [#kynurenic acid]
- KYNA acts as an NMDA receptor antagonist or through the inhibition of the α7 nicotinic acetylcholine (α7nACh) receptors. - [#Bipolar disorder] - in BD > Especially, #GABA, #Glutamate, #Serotonin, #Dopamine, norepinephrine and acetylcholine appears to be importantly dysregulated in these patients
- - only #Lactobacillus plantarum seems to take part in the synthesis of acetylcholine.
- [1.5] [#Lactobacillus plantarum]
- L. plantarum can produce acetylcholine - [1.6]
- #Lactobacillus species produce acetylcholine and #GABA - [1.7] [#Noradrenalin, #Serotonin] [#Keto diet]
- concentrations of 5-HT, NE, AC, and cAMP of SHR in the KD group were strikingly higher than that in the ND group. - [1.8]
- #Acetate metabolism is an important metabolic pathway in many cancers and is controlled by acetyl-CoA synthetase 2 (ACSS2), an enzyme that catalyzes the conversion of #Acetate to acetyl-CoA. - blocking ACSS2, switches #Cancer cells from #Acetate consumers to producers of #Acetate thereby freeing #Acetate for tumor-infiltrating lymphocytes to use as a fuel source.
References Notes
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