Klebsiella ⇒ Klebsiella pneumoniae {10000643}

Shared Reference Notes

• [1.1] 
  - Prior gut infection increases the microbiota’s resistance to subsequent infection. - Sulfide sequestration unleashes endogenous respirers in the gut microbiota. - After infection by K. pneumoniae, the level of the molecule #Taurine rises in the gut. - #Taurine is produced from the metabolism of bile acids. . After infection, resident bacteria that can use #Taurine become more common in the gut.
• [1.2] [#Inflamatory bowel disease] [#Bacteriophage] 
  - Klebsiella pneumoniae (Kp) strains are associated with IBD severity across geography. - A Kp-targeting five-phage combination suppresses intestinal inflammation in IBD models
• [1.3] [#Pneumonia] [#Pseudomonas aeruginosa] 
  - Asymptomatic gut colonisation by Carbapenemase-producing Enterobacterales (CPE) leads to a specific gut dysbiosis and increases the severity of P. aeruginosa lung infection through lower numbers of alveolar macrophages and conventional dendritic cells. - CPE-associated dysbiosis is characterised by a near disappearance of the #Muribaculaceae family and lower levels of short-chain fatty acids.
• [1.4] 
  - sufficient symbiotic microbe protection from #Bacteroidetes could prevent the host-to-host transmission and intestinal colonization of K. pneumoniae
• [#Limosilactobacillus (Lactobacillus) reuteri] [#Short Chain Fatty Acid] - In the K. pneumoniae infection mice model, gut microbial composition (down-regulates Lactobacillus reuteri and #Bifidobacterium pseudolongum) and cecal metabolome (SCFAs) are altered
• [#Inflamatory bowel disease] - saliva K. pneumonia of IBD patients rapidly establishes colonization in mice’s intestines, triggering a strong inflammatory response
• [#Porphyromonas gingivalis] [#Lipopolysaccharide] - Cells of Paneth autonomously sense LPS via MyD88-dependent TLR, then stimulate antimicrobial cytokines and trigger the downstream NF-κB pathway, which subsequently regulates the production of Th17 cells or Tregs (LPS from P. gingivalis induces a stronger Th2 response while Klebsiella pneumoniae induces a stronger Th1 response)
• [1.5] [#Metabolic associated fatty liver disease] [#Alcohol Consumption, #Bacteriophage] 
  - high alcohol-producing Klebsiella pneumoniae (HiAlc Kpn) in the intestinal microbiome could be one of the causes of non-alcoholic fatty liver disease (NAFLD). - treatment with HiAlc Kpn-specific phage was able to alleviate steatohepatitis caused by HiAlc Kpn, including hepatic dysfunction and expression of cytokines and lipogenic genes.
• [1.6] 
  - #Colibactin is a genotoxic secondary metabolite produced by certain strains of gut bacteria, such as #Escherichia coli and Klebsiella pneumoniae. #Colibactin can cause DNA damage and promote the development of #Colorectal cancer .
• [1.7] 
  - #Lactococcus lactis subsp. cremoris, L. lactis subsp. lactis, #Lactobacillus plantarum, #Streptococcus thermophilus, #Escherichia coli, #Morganella morganii, Klebsiella pneumoniae, and #Hafnia alvei produce #Serotonin
• [1.8] [#Staphylococcus epidermidis] 
  - S. epidermidis, #Haemophilus influenzae (H. influenza), and Klebsiella pneumoniae (K. pneumoniae), were suggested to reside in #Lung cancer samples in separate studies
• [1.9] [#Graves’ orbitopathy] 
  - Klebsiella pneumoniae was deemed the potentially pathogenic bacteria of GO, and its abundance was positively correlated with disease severity.
• [#Tryptophan] - #Lactococcus lactis subsp. cremoris (MG 1363), L. lactis subsp. lactis (IL1403), #Lactobacillus plantarum (FI8595), #Streptococcus thermophilus (NCFB2392), #Escherichia coli K-12, #Morganella morganii (NCIMB, 10466), Klebsiella pneumoniae (NCIMB, 673), and #Hafnia alvei (NCIMB, 11999) that can produce #Serotonin from Trp

References Notes