Lactobacillus ⇒ Lactobacillus rhamnosus {10000148}

Shared Reference Notes

• [1.1] [#Probiotic (Bifidobacter and Lactobacilus)] 
  - #Probiotic > #Covid-19 > The proportion who developed symptoms was 26.4% with LGG versus 42.9% with placebo, a significant difference.
• [1.2] [#Atopic Dermatitis] 
  - Supplement Lactobacillus rhamnosus > increase #Butyrate production > reduce atopic symptoms
• [1.3] 
  - Lacticaseibacillus rhamnosus HA-114 is neuroprotective in C. elegans models of #Amyotrophic lateral sclerosis and #Huntington’s Disease. - neuroprotection from L. rhamnosus HA-114 is unique from other L. rhamnosus strains and resides in its fatty acid content. - dietary intervention with L. rhamnosus HA-114 restores lipid homeostasis and energy balance through mitochondrial β-oxidation.
• [1.4] 
  - in pregnant women, supplementation with L. rhamnosus HN001 lead to significantly less postpartum #Depression and #Anxiety
• [1.5] [#Lactobacillus acidophilus, #Staphylococcus aureus] [#Probiotic] 
  - L. rhamnosus did not affect the growth of TSS S. aureus but did inhibit the production of #Toxic shock syndrome toxin-1 (TSST-1) TSST-1; this effect was partially due to acidification of the growth medium. - L. acidophilus was both bactericidal and prevented the production of TSST-1 by S. aureus. This effect appeared to be partially due to acidification of the growth medium, production of H2O2, and production of other antibacterial molecules. - When both organisms were incubated with S. aureus, the effect of L. acidophilus LA-14 dominated.
• [1.6] [#Attention Deficit Hyperactivity Disorder] 
  - Lactobacillus rhamnosus GG decreases the risk of developing ADHD
• [#TNF-alfa] - anti-inflammatory cytokines (IL-4 and #IL-10) and proinflammatory cytokines (TNF-a, #IL-1b, #IL-2, #IL-6, #IL-8, #IL-12, #IL-17, and #IL-18) are significantly changed by Lactobacillus rhamnosus GG (LGG)
• [#TNF-alfa] - Lactobacillus rhamnosus GG is known to strengthen the gut permeability barrier by fortifying intestinal tight junctions, mucin layer thickness, and antigen-specific immunoglobulin A production. - L. rhamnosus GG administrated participants showed a significant decrease in the serum levels of the pro-inflammatory cytokines (#IL-6, #IL-12 p70, and TNF-α).
• [1.7] 
  - #Histamine has potent immunoregulatory effects via #Histamine receptor activation, and there is experimental evidence that an Lactobacillus rhamnosus strain has anti-inflammatory effects via #Histamine receptor activation
• [1.8] 
  - #Allobaculum was highly abundant in the control group as compared to the #Fructose group, and it tended to be more abundant in the L. rhamnosus M9 group.
• [#Bifidobacterium animalis lactis] - #Alloprevotella, increased its abundance in the high-#Fructose treatment but decreased in both the treatment with B. lactis M8 and L. rhamnosus M9.
• [#Hypertension] [#Bifidobacterium animalis lactis] - the probiotics B. lactis M8 and L. rhamnosus M9 significantly reduced BP levels.
• [#Hypertension] - #Coprobacillus and #Butyricimonas, were both more abundant in the L. rhamnosus M9 group as compared to the #Fructose group, which suggests their roles in BP regulation.
• [1.9] [#Systemic lupus erythematosus] [#Lactobacillus delbrueckii] 
  - Compound probiotics (Lactobacillus rhamnosus and Lactobacillus del brueckii) prophylactically fed SLE model mice for 2 months, the levels of related autoantibodies and the frequency of Th1 and Th17 cells in the spleen were decreased; meanwhile, the serum pro-inflammatory factors #IL-17 and IFN-γ levels decreased

References Notes