Lactobacillus ⇒ Lactobacillus oris {10002081} Record Keys Parent:Lactobacillus Definition:Lactobacillus oris Details Initialisation date:[ ] Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - lipid-lowering of probiotics and Lactobacillus oris may be associated with HMGR inhibition to suppress the synthesis of endogenous #Cholesterol; #Bile Acids reabsorption, and intestinal FXR-FGF15 signaling pathways promoting the #Cholesterol conversion into #Bile Acids secretion. [#Metabolic associated fatty liver disease] - Lactobacillus oris treatment increased the expressions of both FXR and SREBP-2 in the liver of mice, suggesting that it might improve NAFLD through the FXR and SREBP pathways. - both intestine ASBT and liver CYP7A were reduced by Lactobacillus oris,References Notes[ ]