Lactobacillus ⇒ Lactobacillus animalis {10000227} Record Keys Parent:Lactobacillus Definition:Lactobacillus animalis Details Initialisation date:2019-08-25 LinksSource Meta Information Rank: Species Domain: Bacteria Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Systemic lupus erythematosus] - Vancomycin-treated mice showed an increase in Lactobacillus animalis in the gut, whereas there was a depletion in the total gut bacterial load. - Oral administration of L. animalis led to an exacerbation of lupus postpartum consisting of worsened splenomegaly and proteinuria while this did not affect the course of the disease in mice that were not pregnant or lactating. - L. animalis acted by inhibiting the serum enzyme indoleamine 2,3-dioxygenase alongside a differential production of immunosuppressive and pro-inflammatory mediators in the postpartum period. - The enriched L. animalis was involved in the vancomycin-driven effects on decreased T regulatory cells and increased pro-inflammatory cytokines. [1.2] [#Obesity] - several bacteria such as: #Methanobrevibacter smithii, #Bifidobacterium spp., #Bifidobacterium animalis, #Escherichia coli, #Akkermansia muciniphila, #Anaerotruncus colihominis and bacteria of the Bacteroidetes strain have the capability to reduce the production of high-calorie substances and therefore also influence the caloric intake. A relatively low frequency of these bacteria correlates with increased body weight, as we have also observed.References Notes[ ]
