Claudin-1 {90000588} Record Keys Parent:[ ] Definition:Claudin-1 Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - sodium #Butyrate (NaB) inhibits NF-κB activation and restores the production of tight junction proteins #ZO-1 and claudin-1 to block the vicious cycle of cytokine storms, improve intestinal barrier function, and increase the survival rate. [1.2] [#Claudin-5, #Zonulin] [1.3] - reduction of membrane localization of tight junction protein (#ZO-1, ZO-2, #Occludin, claudin-1, and -3) and increased permeability in colonocytes were induced by the #Ammonia treatment > mitochondrial dysfunction > increase of #Oxidative stress, > intestinal barrier dysfunction.References Notes[ ]
