Prebiotic {51111432} Record Keys Definition:Prebiotic Queue:[ ] Details Initialisation date:[ ] Specification: [ ] Meta Information Type:Prebiotic Host:[ ] Zone:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Infants, #Milk Formula-feeding] - Prebiotics in formula did increase weight gain but had no impact on length or head circumference gain. - Prebiotics increased stool frequency but had no impact on stool consistency, the incidence of colic, spitting up / regurgitation, crying, restlessness or vomiting. [1.2] - #Lentils (LEN) and #Chickpeas (CKP) increase #Butyrate, while #Inulin (INU) promotes #Propionate. - #Bile Acids and #Cholesterol are reduced in prebiotic groups along with suppressed #Choline-to-trimethylamine conversion by LEN and CKP [1.3] [#Short Chain Fatty Acid] - #Oat β-glucan has demonstrated potential prebiotic properties through its fermentation to SCFAs [1.4] - #Inulin as a prebiotic > increased #Bifidobacterium and #Faecalibacterium prausnitzii, and decreased #Bilophila after #Inulin digestion by human volunteers [1.5] [#Short Chain Fatty Acid] - SCFAs, the products of prebiotic fermentation, could induce the expression of #Tyrosine hydroxylase [1.6] - Prebiotic interventions are the most likely to result in changes to gut microbiome composition, followed by dietary interventions, and then #Probiotic interventions [1.7] [#Cancer] - The #Polysaccharide FMP-1 derived from #Morchella esculenta is attributed with prebiotic benefits and potential anti-tumor activity owing to its antioxidant capabilities [1.8] [#Short Chain Fatty Acid] - Dietary rhamnogalacturonan-I obtained by enzymatic treatment of #Carrot pomace has shown prebiotic properties. - cRG-I was degraded rapidly in the proximal colon compartment and fermentation became quicker and more complete during three weeks of repeated supplementation. - arabinan sidechains were utilized before the RG-I backbone, which correlated with an increase in #Bifidobacterium longum absolute abundance over the three weeks period. - Donor specific production of all SCFA increased over time with a general trend of higher levels of #Acetate and #Propionate than #Butyrate. [1.9] [#Inflamatory bowel disease] [#Flavonoid] - #Broccoli, #Kale, radish, and #Cabbage are flavonoids-rich with #Quercetin and cyanidin, and #Polyphenols like ferulic, sinapic, and caffeic acids for prebiotic, endothelial and epithelial barrier protection, antioxidant, anti-inflammatory and anti-adhesive potential to complement the effect of ITCs against IBD [#Short Chain Fatty Acid] [#Probiotic] - A 12-week multi-species synbiotic supplementation in patients with #Dyslipidemia resulted in significant increases in fecal SCFAs including #Acetate, #Butyrate, #Propionate, and #Valerate in the intervention group.References Notes[ ]
