Combination of probiotics and polyphenol-rich prebiotics {51111263} Record Keys Definition:Combination of probiotics and polyphenol-rich prebiotics Queue:[ ] Details Initialisation date:2022-01-09 Specification: [ ] Meta Information Type:Prebiotic, Probiotic Host: Mouse Zone:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Depression] - Combination of probiotics and polyphenol-rich prebiotics, a synbiotic >attenuates the chronic-stress induced inflammatory responses in the ileum and the prefrontal cortex promoting > resilience to the consequent depressive- and #Anxiety-like behaviors in male mice. - This effect may be attributed to specific synbiotic-produced metabolites including #4-hydroxyphenylpropionic, #4-hydroxyphenylacetic acid and #Caffeic acid > promoted anti-inflammatory activity through the aryl hydrocarbon receptor (AHR). [1.2] [#Depression] [#Bifidobacterium animalis lactis, #Bifidobacterium bifidum, #Bifidobacterium longum, #Lactobacillus acidophilus] [#humanized Galactooligosaccharides] - patients were administered a synbiotic containing L. acidophilus, B. bifidum, B. lactis, and B. longum with the prebiotics FOS, GOS and #Inulin. In a subset of patients with depressive symptoms, the synbiotic significantly reduced the depressive score compared to both the #Probiotic-alone and placebo groups, which correlated to an increase in #BDNF serum levels.References Notes[ ]
