C-reactive protein {90000314} Record Keys Parent:[ ] Definition:C-reactive protein Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Depression] - chronic psychological or physical stress induce a battery of depressive phenotypes through mechanisms related to abnormalities in hypothalamic-pituitary-adrenal (HPA) axis signaling including hypersecretion of C-reactive protein from the hypothalamus, impaired negative feedback of the HPA axis and hypercortisolemia. [1.2] [#High Fat Diet, #Low Fat Diet] - #Gluten, when added to the LFD, increases circulating C-reactive protein levels. - #Gluten regardless of whether it was added to LFD or HFD led to a profound increase in the number of microglia and astrocytes in the arcuate nucleus of the hypothalamus, as detected by immunohistochemistry for ionised calcium binding adaptor molecule 1 (Iba-1) and glial fibrillary acidic protein (GFAP), respectively. [1.3] [#humanized Galactooligosaccharides] - GOS increased the blood level of interleukin 8 (#IL-8), interleukin 10 (#IL-10), and C-reactive protein in adults, but decreased IL-1β. It has been found that the function of NK cells improves by consuming GOS. [1.4] [#Inflamatory bowel disease] - IBD is associated with several biochemical and hematological changes, which are often used to support the diagnostic process, including vitamin and mineral deficiencies,13,14 anemia,15 increases in inflammatory markers, including C-reactive protein (CRP) and fecal #Calprotectin (f-cal), and/or clinically measurable manifestations of associated liver disease. - the median values for all blood test results (indeed, all test results apart from fecal #Calprotectin) were within their respective normal ranges [1.5] [#Tryptophan] - serum Trp levels across the majority of Chronic inflammatory diseases (CIDs), and a prevailing negative relationship between Trp and systemic inflammatory marker C-reactive protein (CRP). - serum Trp was low in several CIDs even in the absence of measurable systemic inflammation. - Increases in the #kynurenine-to-Trp ratio (Kyn:Trp) suggest that these changes result from increased degradation along the #kynurenine pathway.References Notes[ ]
