Methanobacteriaceae ⇒ Methanobrevibacter {10000301} Record Keys Parent:Methanobacteriaceae Definition:Methanobrevibacter Details Initialisation date:2020-10-13 Meta Information Rank: Genus Domain:Archaea Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Alzheimer’s disease, #Amyotrophic lateral sclerosis, #Multiple Sclerosis] - ALS appeared to be less associated with microbial dysbiosis compared to MS and AD, with only one microbe genus, Methanobrevibacter and #Ruminococcaceae being commonly present under elevated conditions, respectively. [1.2] [#Gestational Hypertension, #Preeclamsia] - the relative abundance of Methanobrevibacter is higher in healthy controls than in HDP cases during both early and late pregnancies. [#Preeclamsia] - Methanobrevibacter is negatively correlated with PE and this association is still significant after adjusting for covariates such as alcohol drinking, smoking, and T2D. [#Preeclamsia] - the methanogenesis pathway mediated by Methanobrevibacter has been shown to reduce serum #TMAO levels, thereby reducing the risk of PE [1.3] - Methanobrevibacter, is represented by two major species, which modulate the host’s nutrient break-down. [1.4] - Methanobrevibacter-associated microbial communities are linked with skeletal markers of systemic diseases (for example, periostitis and joint pathologies), and their disappearance is consistent with temporal shifts, including the arrival of the Second Plague #Pandemic. [#Natural oral microbiomes] - Ancient dental calculus > multiple oral microbial communities that coexisted in Britain for millennia, including a community associated with Methanobrevibacter, an anaerobic #Archaea not commonly prevalent in the oral microbiome of modern industrialized societies. [1.5] [#mRNA vaccine] - Methanobrevibacter, #Ruminococcaceae #DTU089, #Marvinbryantia, #Cloacibacillus, and #Succinivibrio were enriched in the baseline microbiome of individuals with low IgG titers and low spike-specific CD4+ T-cell responses. [#Covid-19] [#mRNA vaccine] - high spike IgG levels, with less abundance of bacterial groups belonging to #Clostridiales and #Methanobacteriales, such as #Ruminococcaceae #DTU089 and Methanobrevibacter, respectively. References Notes[ ]
