Branched short-chain fatty acids ⇒ Isovaleric acid {90000367}
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Definition: | Isovaleric acid |
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Shared Reference Notes
- [1.1]
- Fecal levels of isovaleric acid positively correlated with an average of morning and mid-day salivary cortisol measurements. - #Depression symptoms positively correlated with fecal levels of isovaleric acid - [1.2] [#Branched short-chain fatty acids, #Isobutyric acid] [#High-protein diet]
- Both isobutyric and isovaleric acids are BSCFAs, which are produced by fermentation of #Branched-chain amino acids by intestinal flora. Milk and dairy products are unique dietary sources of BCFAs. - Higher levels of BCFAs are produced when eating a high-protein/low-carbohydrate diet - [1.3]
- norepinephrine, indole, #Indole-3-aldehyde, isovaleric acid, #Butyric acid, and #Isobutyric acid stimulate #Serotonin release from enterochromaffin cells. - [1.4] [#Cancer] [#Acetic acid, #Butyric acid, #Isobutyric acid, #Isocaproic acid]
- aciduric #Peptostreptococcus stomatis produces acetic, butyric, isobutyric, isovaleric, and isocaproic acids. - Production of such acids may contribute to the acidic and hypoxic microenvironment of tumors, thereby increasing metastatic efficiency - [1.5] [#Autism] [#Caproic acid, #Isobutyric acid, #Propionic acid, #Short Chain Fatty Acid, #Valeric acid]
- higher levels of propionic and valeric acids as well as the sum of minor SCFA (isobutyric + isovaleric + valeric + caproic acids) were found in ASD at the age 4–7 years, but these differences disappeared at the age of 8–10 year
References Notes
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