Porphyromonas ⇒ Porphyromonas asaccharolytica {10000291} Record Keys Parent:Porphyromonas Definition:Porphyromonas asaccharolytica Details Initialisation date:2020-10-12 Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Corynebacterium amycolatum, #Corynebacterium Lactis, #Porphyromonas bennonis, #Porphyromonas somerae, #Prevotella birria, #Prevotella buccalis, #Prevotella disiens, #Prevotella timonensis] - These trios have been speculated as an opportunistic group with specific species of C. amycolatum, C. lactis of genus Corynebacterium, P. asaccharolytica, P. bennonis, P. somerae, P. unonis of genus Porphyromonas and P. birria, P. buccalis, P. disiens, P. timonensis of genus Prevotella, which are drastically altered in PD [1.2] [#Parkinson’s Disease] [#Lipopolysaccharide] - of the 29 species that are reduced in PD, only 1 is a canonical Gram-negative organism, #Prevotella copri, which interestingly, produces an LPS that not only does not induce inflammation, but can inhibit TLR4 activation by others. - Eleven of the 55 species that are enriched in PD are canonical Gram-negative organisms including those with highly stimulatory LPS (#Escherichia coli, #Klebsiella species, and Porphyromonas asaccharolytica). [1.3] [#Colorectal cancer] - #Fusobacterium nucleatum, did not significantly associate with CRC diagnostic groups (healthy, adenoma and carcinoma) when controlling for covariates transit time, fecal #Calprotectin (intestinal inflammation) and body mass index as primary microbial covariates. - In contrast, the associations of #Anaerococcus vaginalis, #Dialister pneumosintes, #Parvimonas micra, #Peptostreptococcus anaerobius, Porphyromonas asaccharolytica and #Prevotella intermedia remained robust, highlighting their future target potential. References Notes (200) [1.5]
