Indole-3-lactic acid {90000346} Record Keys Parent:[ ] Definition:Indole-3-lactic acid Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Indole-3-carboxyaldehyde, #Indole-3-propionic acid, #Niacin, #Tryptophan] [#Ginseng] - #Ginsenoside Rg1 could increase the levels of Trp metabolites in the serum, including indole-3-carboxaldehyde, indole-3-lactic acid, 3-indolepropionic acid and niacinamide. - In mice with high-fat diet-induced obesity, #Ginsenoside Rb1 significantly altered the gut microbiota composition and serum Trp [#Indole-3-acetamide (IAM), #Indole-3-acetic acid, #Indole-3-aldehyde, #Indole-3-propionic acid, #Indole-3-pyruvic acid (IPyA), #Indoleacrylic acid (IA)] - For AhR, the most effective Trp metabolites are #Indole, #Skatole, IA, #Tryptamine, IPyA and #Indole-3-acetamide (IAM), whereas IAA, IAID, IPA and ILA are the least active [1.2] [#Chronic fatigue syndrome] [#γ-butyrobetaine] - Indole-3-lactate and γ-butyrobetaine were also reduced in the all ME/CFS group but were not amongst the top 10 plasma biomarkers. [1.3] [#GABA, #Human milk oligosaccharides] [#Adult] - Indole-3-lactic acid and #3-phenyllactic acid (linked to immune health) and gamma-aminobutyric acid (linked to gut-brain axis) were most profoundly stimulated by 2′FL and HMO blends in both #Children and adults, correlating with specific #Bifidobacteriaceae. [1.4] [#Indole-3-propionic acid] - #Clostridium sporogenes, for example, converts #Tryptophan into #Tryptamine, indoleacetic acid (ILA), and #Indole #Propionic acid (IPA) [1.5] [#Multiple Sclerosis] [#Indole 3-acetat ] - MS > the elevated ratio of indole 3-acetate to ILA in MS is associated with increased disease severity. [#Multiple Sclerosis] - supplementation of ILA reduced neuroinflammation and promoted remyelination in MS. [#Multiple Sclerosis] - MS > there is a notable decrease in circulating #Indole 3-#Lactate (ILA), having a more pronounced reduction in progressive forms compared with relapsing-remitting disease. [1.6] - indole-3-lactic acid (ILA) is able to reduce inflammation in immature epithelial cellsReferences Notes[ ]
