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Microbiome & Chronic Diseases

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Synergistales ⇒ EBV {10001484}

Record Keys


Parent:
Definition:
EBV

Details


Initialisation date:
2022-01-17

Meta Information


Rank:
 Family
Domain:
 Bacteria
Zone:[  ]
Enzyme:[  ]
Function:[  ]

Notes:


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Shared Reference Notes


  • [1.1] [#Multiple Sclerosis
    - Risk of MS increased 32-fold after infection with EBV but was not increased after infection with other viruses, including the similarly transmitted cytomegalovirus. - Serum levels of neurofilament light chain, a biomarker of neuroaxonal degeneration, increased only after EBV seroconversion.
  • [1.2] [#Chronic fatigue syndrome
    - Up to 37% of ME/CFS patients reported a past symptomatic EBV infection
  • [1.3] [#Esophageal cancer
    - infections #HPV and EBV reportedly increased risk of esophageal squamous cell carcinoma
  • [#Gastric carcinoma] - EBV integrates its DNA into the host, expresses latent protein, and then impairs methylation of DNA via miRNA under the action of the latent protein, resulting in EBV-positive gastric cancer.
  • [1.4
    - definitive association between an increased risk of #Multiple Sclerosis and prior infection with the Epstein-Barr virus (EBV).

References Notes


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