Synergistales ⇒ EBV {10001484} Record Keys Parent:Synergistales Definition:EBV Details Initialisation date:2022-01-17 Meta Information Rank: Family Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Multiple Sclerosis] - Risk of MS increased 32-fold after infection with EBV but was not increased after infection with other viruses, including the similarly transmitted cytomegalovirus. - Serum levels of neurofilament light chain, a biomarker of neuroaxonal degeneration, increased only after EBV seroconversion. [1.2] [#Chronic fatigue syndrome] - Up to 37% of ME/CFS patients reported a past symptomatic EBV infection [1.3] [#Esophageal cancer] - infections #HPV and EBV reportedly increased risk of esophageal squamous cell carcinoma [#Gastric carcinoma] - EBV integrates its DNA into the host, expresses latent protein, and then impairs methylation of DNA via miRNA under the action of the latent protein, resulting in EBV-positive gastric cancer. [1.4] - definitive association between an increased risk of #Multiple Sclerosis and prior infection with the Epstein-Barr virus (EBV).References Notes[ ]