Oxygen {51111343}

Record Keys


Definition:
Oxygen
Queue:[  ]

Details


Initialisation date:
2022-08-25
Specification:
[  ]

Meta Information


Type:
Environment
Host:
 Human
Zone:[  ]

Notes:


Extremely oxygen sensitive (EOS) Microbiota

Shared Reference Notes


  • [1.1
    - GutAlive maintained extremely oxygen sensitive (EOS) populations that were lost in conventional stool containers, and thus viability of species such as as #Akkermansia muciniphila, #Faecalibacterium prausnitzii and a novel member of the #Clostridiales order was kept.
  • [1.2] [#Candida albicans
    - the presence of C. albicans alters the bacterial microbiota, leading to the presence of strictly anaerobic bacteria when oxygen is abundant.
  • [1.3
    - Oxygen radicals might be produced through the cascade of #Homocysteine metabolism causing endothelial cell damage, and #Homocysteine could activate matrix metaroproteinase-9, a membrane disrupting agent, leading to a direct influence on the cell membrane. - about 25% of systemic circulating #Homocysteine is produced by intestinal mucosal cells
  • [1.4
    - Lipid peroxidation (LPO) in the cell membranes has been recognized as the major mechanism of tissue impairment due to #Oxidative stress. - #Malondialdehyde is an end-product of LPO, which is an indicator of tissue injury mediated by free oxygen radicals. - Lipid peroxidation is more important than protein peroxidation in the pathogenesis of #Melasma.
  • [1.5
    - #Hydrogen sulfide may suppress the oxygen-dependent metabolism of some pathogens - #Taurinivorans muris has a protective role against #Klebsiella and #Salmonella, two important gut pathogens.
  • [1.6
    - During the state of ischemia, the absence of oxygen induces a reduction in mitochondrial respiration and a rise in the accumulation of #Succinate.
  • [1.7] [#Colitis] [#Para-cresol
    - When p-cresol presents in excess in colonocytes, it inhibits mitochondrial oxygen consumption and consequently reduces cell proliferation. - when colonocytes were treated with p-cresol, anion superoxide production and DNA-double strand break were increased; thus, p-cresol is genotoxic.
  • [1.8] [#Plant Microbiome
    - to the presence of oxygen in the newborn gut,Citation37 facultative anaerobic #Gammaproteobacteria i.e., #Pantoea, #Erwinia, and #Acinetobacter which originate from fruit and vegetables can colonize in the gut of #Infants during the early weaning period.
  • [#Infants] - due to the reduced oxygen concentration,Citation38 anaerobic #Bacteria, i.e., Lentilactobacillus and #Lactobacillus, emerge during the 8th to 12th month.
  • [1.9] [#Intermittent Hypoxia
    - IH affects the arterial partial pressure of oxygen, which could result in a hypoxia/reoxygenation pattern within the gut

References Notes


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Common References


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