Disease ⇒ Melasma {40000617} Record Keys Type:Disease Parent:[ ] Definition:Melasma Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - Lipid peroxidation (LPO) in the cell membranes has been recognized as the major mechanism of tissue impairment due to #Oxidative stress. - #Malondialdehyde is an end-product of LPO, which is an indicator of tissue injury mediated by free #Oxygen radicals. - Lipid peroxidation is more important than protein peroxidation in the pathogenesis of melasma.References Notes[ ]