Microbiome & Chronic Diseases

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Branched-chain fatty acids ⇒ Leucine {60000107}

Record Keys

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Initialisation date:

- The most important ketogenic amino acid in humans.
- Stimulate mTOR signaling.
- Precursor of acetyl-CoA.


meats, dairy products, soy products, beans, other legumes

Meta Information

Structural Type:
Amino acid
Functional Type:[  ]
Function:[  ]


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Shared Reference Notes

  • [1.1] [#Anorexia nervosa] [#Bacteroides vulgatus
    - in AN > Serum leucine mediated the influence of B. vulgatus counts on #Glucose homeostasis.
  • [1.2] [#Soybean
    - Soybeans contain around twice the amount of protein compared to other commonly consumed beans and legumes, and are the only plant source that contains all nine essential amino acids. The leucine content of soybeans is comparable to levels found in fish and eggs.
  • [1.3
    - Amino acids including #Phenylalanine, lysine, #Tryptophan, #Valine, leucine, and #Isoleucine, which are not synthesized in the body, were all reduced in individuals with #Obesity. - The reasons might be that specific amino acids were derived from proteins of various foods and fermented by microbiotas, which caused the concentration change in the circulation.
  • [1.4] [#Autism
    - Autistic children were less likely to consume foods high in #Glutamic acid, serine, #Choline, #Phenylalanine, leucine, #Tyrosine, #Valine and #Histidine, all compounds involved in neurotransmitter biosynthesis

References Notes

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