Branched-chain fatty acids {90000326}
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| Definition: | Branched-chain fatty acids |
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BCFAs | |
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Shared Reference Notes
- [1.1]
- branched-chain fatty acids (BCFAs) such as valine, leucine, and isoleucine) have been found in much lower amounts in rodent and human GI tracts - [1.2] [#Gastric bypass surgery]
- RYGB surgery > the fecal concentrations of two BCFAs—#Isobutyrate and #Isovalerate—increased after surgery - [#Secondary bile acids] - Roux-en-Y #Gastric bypass surgery (RYGB) > The changes in the fecal microbiome were linked to increased concentrations of branched-chain fatty acids and an overall decrease in secondary bile acid concentrations. - RYGB surgery also increased bile acid concentrations in plasma
- [1.3]
- BCFAs have strong anti-inflammatory potential and may have a beneficial effect on insulin sensitivity in humans. - BCFAs can reduce the expression level of genes encoding proinflammatory proteins in a dose-dependent manner to play an anti-inflammatory role.
References Notes
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