Isoflavone {90000356}

Shared Reference Notes

• [1.1] [#Lipopolysaccharide] [#Isoflavone diet, #Phytoestrogen-free (phyto-free) diet] 
  - LPS extracted from feces of mice fed an ISO diet induced increased production of anti-inflammatory cytokines from bone marrow-derived macrophages relative to fecal-LPS isolated from mice fed a PF diet.
• [1.2] [#Phytoestrogen] 
  - gut bacteria can metabolize isoflavones into #Equol, which has a higher affinity for endogenous estrogen receptors compared to dietary isoflavones. - isoflavone-rich diet can protect from neuroinflammatory diseases, and that protection was dependent on the ability of gut bacteria to metabolize isoflavones into #Equol. - mice on a diet with isoflavones showed an anti-inflammatory response compared to the mice on a diet lacking isoflavones.

References Notes