UV radiation {51111397} Record Keys Definition:UV radiation Queue:[ ] Details Initialisation date:[ ] Specification: [ ] Meta Information Type:[ ] Host:[ ] Zone:[ ] Notes: [ ]Shared Reference Notes [1.1] - #Lactobacillus plantarum HY7714, #Bifidobacterium breve B-3 > skin protection. - there were functional substances in the skin–gut axis communication, which interact in a photoprotective manner, resulting in an anti-#Aging effect in a mouse model, and administration of #Lactobacillus plantarum HY7714 can decrease the symptoms of UV-induced skin photo-#Aging in humans. - #Lactic acid secreted by Lactobacillus reuteri DSM 17,938 can protect skin from UVB by suppressing pro-inflammatory #IL-6 and IL-8 cytokines. - #Lactobacillus plantarum had the potential to prevent UV-induced photoaging by inhibiting MMP-1 expression in fibroblast in mice. [#Natural Skin Microbiome] - The generation of #Reactive Oxygen Species secondary to normal aerobic metabolism, and exogenous factors, such as UV radiation, is the main cause of skin #Aging [1.2] - #Sphingomonas and #Erythrobacteraceae, may have the ability to protect against UV radiation as they produce potentially protective compounds. Indeed, further analysis showed that a #Sphingomonas spp. was able to reduce #Reactive Oxygen Species levels in human keratinocytes. [1.3] [#Ultraviolet Exposure] - #Propionic acid reduced UVB (Ultraviolet B)-induced functioning melanocyte levels by inhibiting tyrosinase activity in vitro and in vivo [1.4] - Among these diverse biological effects of #Resveratrol, the antioxidant properties are most prominent. - #Resveratrol has been shown to protect cells against #Hydrogen peroxide-induced #Oxidative stress, as well as UV-irradiation-mediated cell death. - Chronic UV exposure induces #Reactive Oxygen Species (ROS) production, activating three major #Skin aging cascades. - Resveratrol > prevent photo-#Aging through anti-inflammatory, antioxidant, and antitumour pathways. - The viability of cultured human keratinocytes (HaCaT cell line) pretreated with different doses of resveratrol significantly increased up to 94%. [#Skin aging] - In mice > oral or topical administration of #Resveratrol resulted in a suppression of UVB-induced epidermal thickening.References Notes[ ]
