Riboflavin [Vitamin B2] {90000412} Record Keys Parent:[ ] Definition:Riboflavin Queue:Vitamin B2 Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:Vitamin Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - riboflavin supplementation increased the abundance of bacteria that cannot synthesize riboflavin, such as #Faecalibacterium prausnitzii and #Roseburia spp. - Higher intake was also associated with an increase in the abundance of #Prevotella spp. [#Faecalibacterium prausnitzii] - riboflavin, act as a redox mediator and stimulate the growth of auxotrophic bacteria such as Faecaibacterium prausnitsii - A complete riboflavin operon is present in all Baceteroidetes and #Fusobacteria, as well as in 92% of #Proteobacteria - half of the #Firmicutes are predicted to be riboflavin producers - Human gut microbiota can produce riboflavin, primarily in the large intestine - riboflavin is also required for the postnatal development of the gastrointestinal tract. Its deficiency was associated with crypt hypertrophy, interruptions in crypt bifurcation in rats [1.2] [#Crohn’s disease] [#Candida albicans] [#Thiamin] - Ca albicans is largely overrepresented in inflammatory (B1) vs stricturing (B2) phenotypes, and it is actually the only species showing significant differences. - An increased abundance of Ca albicans in inflammatory CD (B1) is consistent with its proinflammatory effects described in several studies. [1.3] [#Meat-based diet] - #D-ribose (RIB) is a naturally occurring monosaccharide that is found in riboflavin-containing foods such as #Wheat bran, eggs, and meat.References Notes[ ]