Colectomy {51111444} Record Keys Definition:Colectomy Queue:[ ] Details Initialisation date:[ ] Specification: [ ] Meta Information Type:[ ] Host:[ ] Zone:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Crohn’s disease] - in CD patients > Six months after surgery, ten patients developed recurrence of CD lesions. Samples collected at time of surgery were enriched in #Proteobacteria and harbored high levels of unusual, bacteria such as #Streptococcus mitis, #Undibacterium oligocarboniphilum, #Sphingomonas melonis and #Gemella haemolysans, while 6 months after surgery samples had elevated proportions of anaerobic bacteria belonging to #Lachnospiraceae (#Clostridium nexile, #Blautia wexlereae, #Dorea longicatena). Remission was characterized by increased levels of bacteria belonging to Bacteroides, Dorea, Ruminococcus and Dialister genera, whereas recurrence was associated with increased levels of #Gemmiger formicilis, #Enterococcus durans and #Ruminococcus lactaris. [#Inflamatory bowel disease] [#Escherichia coli] - Colectomy > there was a significant increase in the expansion of E.coli in individuals who underwent surgery and, in particular, samples from IBD patients who underwent colectomy had the highest abundance of E.coli. - At 6 months, endoscopic recurrence was associated with elevated #Proteus genera and at 18 months with reduced #Faecalibacterium, #Desulfovibrio and #Bilophila abundance. At 18 months severe endoscopic recurrence was associated with increase in #Proteobacteria.References Notes[ ]
