Citrobacter ⇒ Citrobacter rodentium {10000222}
Parent: | |
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Definition: | Citrobacter rodentium |
Initialisation date: | 2019-08-10 |
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Rank: | Species |
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Domain: | Bacteria |
Zone: | [ ] |
Enzyme: | [ ] |
Function: | [ ] |
Notes:
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Shared Reference Notes
- [1.1]
- Switching mice from a standard grain-based rodent chow to a high-fat, low-fiber #Western-style diet resulted in a rapid reduction in the number of gut bacteria. - Mice fed the #Western-style diet were frequently unable to clear the pathogen Citrobacter rodentium from the colon. They were also prone to developing chronic infection when re-challenged by this pathogen. - [1.2] [#Pectin]
- Pectins > anti-inflammatory properties on intestinal immunity > direct interactions on Toll-like receptors (TLRs) in the small intestine or via stimulating microbiota-dependent effects in the large intestine. - Pectins> prevent C. rodentium induced colonic inflammation > lowering the C. rodentium load in the caecum independently of the DB. - [1.3] [#Vitamin A]
- Commensal segmented filamentous bacteria protect against C. rodentium infection - Commensal bacteria express enzymes that generate #Retinoic acid in the intestine - Commensal bacterial-derived #Retinoic acid promotes epithelial defense in the host
References Notes
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