Chlorogenic acid {90000435} Record Keys Parent:[ ] Definition:Chlorogenic acid Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Bifidobacterium animalis] - B. animalis > ester hydrolysis of chlorogenic acid to release #Caffeic acid. - Roasted green #Coffee beans contain a high level of #Hydroxycinnamates, which are partially bioavailable yet extensively metabolized, mainly by the colonic microbiota. - In subjects who drank a roasted #Coffee blend containing 269.5 mg of chlorogenic acids, the majority of metabolites in the urine (75.7%), composed of #Dihydrohydroxycinnamic acids and #Feruloylglycine, were of colonic origin. [#Lactobacillus plantarum, #Streptococcus thermophilus] [#Cypto-chlorogenic acid] - mulberry #Anthocyanins were specifically transformed by S. thermophilus (46.2%) and L. plantarum (43.6%) into chlorogenic acid, cypto-chlorogenic acid, #Caffeic acid and #Ferulic acid: all #Phenolic acids with potent anti-inflammatory benefits. [1.2] - Chlorogenic acid has also shown to mitigate DSS-induced #Colitis in mice by inhibiting M1 macrophage polarization through suppressing PKM2-dependent glycolysis and Nod-like receptor protein 3 activationReferences Notes[ ]
