Inulin {50000153} Record Keys Definition:Inulin Queue:[ ] Details Initialisation date:2020-10-17 Specification: [ ] Meta Information Type:Diet, Prebiotic Host:[ ] Zone:[ ] Notes: - Ingestion of inulin led to a significant stimulation of Bifidobacterium adolescentis relative to the whole microbiota. (1)Shared Reference Notes [1.1] - LCI is associated with an increase in #Bifidobacterium. [#Elevation of alanine aminotransferase (ALT)] - High doses of inulin cause inflammation and elevation of alanine aminotransferase (ALT) [1.2] [#Allergy] - diet of inulin fibre alters the composition of the mouse microbiota and the levels of microbiota-derived metabolites, notably #Bile Acids. - This metabolomic shift is associated with type 2 inflammation in the intestine and lungs, characterized by IL-33 production, activation of group 2 innate lymphoid cells and eosinophilia. - dietary inulin fibre triggers microbiota-derived #Cholic acid and type 2 inflammation at barrier surfaces [1.3] [#Acetate, #Butyrate, #Propionate, #Short Chain Fatty Acid] - inulin and #Rice bran promoted the production of all three SCFA - Inulin > increase genera #Blautia, #Anaerostipes, and #Bifidobacterium [#Maltodextrin, #Resistant starch, #Rice] - The relative abundance of the pro-inflammatory phylum #Proteobacteria was decreased by the prebiotic intervention [#Short Chain Fatty Acid] - Resistant #Maltodextrin and inulin produced the greatest increase in total SCFA levels followed by #Resistant starch and #Rice branReferences Notes[ ]
