Disease ⇒ Hyperglycemia {40000478} Record Keys Type:Disease Parent:[ ] Definition:Hyperglycemia Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:10020635 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Clostridium sporogenes] [#Tryptophan] - Two gut #Bacteria C. sporogenes and #Ruminococcus gnavus can convert Trp into #Tryptamine which is able to inhibit #Glucose-induced hyperglycemia and enhance insulin release. [1.2] [#Diabetes Type 2] - #Resveratrol also showed promising potential for the treatment of #Diabetic ulcers. - #Resveratrol prevented hyperglycemia-induced endothelial dysfunction and angiogenic impairment by activating endothelial SIRT1 and promoting forkhead box O1 (FOXO1) degradation, following a de-repression of c-Myc expression. [1.3] - Distinct VOC signatures for #Schizophrenia were m/z 60 and m/z 74. The first of these was identified as trimethylamine (#TMA). - patients with #Schizophrenia displayed a significantly lower concentration of #TMA in their breath. - Decreased production of #TMA is found in patients with #Choline-deficient diets, in nonalcoholic #Steatohepatitis and may result in #Obesity and hyperglycemia, which are often seen in patients with #Schizophrenia.References Notes[ ]
