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Palmitoleic acid {90000278}

Record Keys


Biotic:
Palmitoleic acid
Parent:[  ]
Queue:[  ]

Details


Initialisation date:
2022-03-15
Specification:
[  ]
Source:
[  ]

Meta Information


Structural Type:[  ]
Functional Type:[  ]
Function:
Anti-inflammatory

Notes:


[  ]

Shared Notes


  • [1.1
    - Oral treatment of A. muciniphila or A. muciniphila-mediated palmitoleic acid strongly inhibits tuberculosis infection through epigenetic inhibition of tumour necrosis factor in mice infected with Mycobacterium tuberculosis.
  • - single-nucleotide polymorphism rs2257167 ‘G’ allele of type I interferon receptor 1 (encoded by IFNAR1 in humans) contributes to stronger type I interferon signalling, impaired colonization and abundance of A. muciniphila, reduced palmitoleic acid production, higher levels of tumour necrosis factor, and more severe tuberculosis disease in humans and transgenic mice