Palmitoleic acid {90000278}
| Biotic: | Palmitoleic acid |
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| Parent: | [ ] |
| Queue: | [ ] |
| Initialisation date: | 2022-03-15 |
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| Specification: | |
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| Source: | |
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| Structural Type: | [ ] |
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| Functional Type: | [ ] |
| Function: | Anti-inflammatory |
Notes:
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Shared Notes
- [1.1]
- Oral treatment of A. muciniphila or A. muciniphila-mediated palmitoleic acid strongly inhibits tuberculosis infection through epigenetic inhibition of tumour necrosis factor in mice infected with Mycobacterium tuberculosis. - - single-nucleotide polymorphism rs2257167 ‘G’ allele of type I interferon receptor 1 (encoded by IFNAR1 in humans) contributes to stronger type I interferon signalling, impaired colonization and abundance of A. muciniphila, reduced palmitoleic acid production, higher levels of tumour necrosis factor, and more severe tuberculosis disease in humans and transgenic mice