Ellagitannins {90000308}
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| Definition: | Ellagitannins |
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| Function: | Anti-inflammatory |
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Shared Reference Notes
- [1.1]
- Ellagic tannins, in pomegranate and grape, are not bioavailable but intestinal microbes can convert them into #Urolithins with antioxidant activity and preventive effects for chronic diseases such as cancer, diabetes, and cardiovascular and neurodegenerative diseases - [1.2]
- microbial-derived #Urolithins have potent anti-inflammatory effects. In human colonic fibroblasts, #Urolithins, but not their ellagitannin precursor, inhibited nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) translocation into the nucleus and consequent activation of downstream inflammatory events. - [#Gordonibacter pamelaeae] - The #Urolithins are an important class of bioactive microbial metabolites derived from ellagitannin and #Ellagic acid precursors. - Several bacterial species have been identified that produce their intermediate metabolites including #Gordonibacter urolithinfaciens and G. pamelaeae.
References Notes
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