Sulforaphane {90000231}

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Shared Reference Notes

  • [1.1
    - Sulforaphane can normalize the intestinal flora imbalance of #Bladder cancer mice with a significant increase in #Bacteroides fragilis and #Clostridium cluster I
  • [1.2
    - Sulforaphane is a naturally occurring, potent antioxidant, found in Brassicaceae plants such as #Broccoli, and is being considered for use in the treatment of #Fibrosis, #Cancer and preeclampsia
  • - Under anaerobic conditions, the enteropathogenic #Escherichia coli strain EPEC E2348/69 showed the most significant increases in growth in the presence of sulforaphane. - In aerobic conditions, sulforaphane was shown to have an antimicrobial effect on EPEC E. coli ECE2348/69 - decrease in oxygen concentration, sulforaphane may not provide antioxidant functions
  • [1.3] [#Cruciferous vegetables
    - Cruciferous diet can supply GSLs such as glucoraphanin (GLR), sinigrin, and glucoerucin, which are metabolized by plant-sourced myrosinase and gut microbiota-sourced enzymes into isothiocyanates (ITCs), such as sulforaphane (SFN) and erucin

References Notes

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